On October 25, 2024, the Fourth Session of the First Council and the 2024 Annual Academic Conference of the Sichuan Bioinformatics Society were successfully held in Chengdu! This grand event gathered more than 300 outstanding experts and scholars from the fields of bioinformatics and smart medicine from all over the country. They gathered in the land of abundance to deeply discuss the latest research results, future development trends, and challenges in the field of intelligent medicine, aiming to strengthen academic exchanges, promote industry-academia-research cooperation, and further promote the development of translational medical informatics in China.

 The Fourth Session of the First Council and the General Assembly of Members of the Sichuan Bioinformatics Society was successfully held under the chairmanship of the society's deputy secretary-general, Zhou Jueqiao.

 The conference heard the 2024 work summary and 2025 work plan from Shen Bairong, the president of Sichuan Bioinformatics Society. President Shen's report showcased the society's achievements over the past year and the direction for the future. In the coming year, we also face new challenges and opportunities. The 2025 work plan will guide us and motivate us to continue moving forward.

 The conference reviewed the financial work report presented by Yang Yin, the deputy secretary-general of the society. Financial transparency is an important safeguard for our work, and a healthy financial condition is the foundation for the society's continuous development.

 The conference reviewed the motion to revise the "Sichuan Bioinformatics Society Constitution" proposed by Professor Tang Hua, a standing director of the society. The perfection of the constitution will provide a more solid legal basis for our organization. We look forward to this revision to make the society's operations more standardized and better serve the majority of members and the development of the bioinformatics field.

 Talent is the core of the society's development. The conference reviewed the motion on the appointment of society staff proposed by Deputy Secretary-General Shi Zheng. He not only focuses on the candidates' professional background and academic achievements but also pays attention to their contributions to the strategic planning and innovative thinking for the future development of the society.

 The conference reviewed the 2024 Advanced Review Plan proposed by Huang Jian, the vice president of the society. This plan will motivate each of our members to contribute more to the development of the society. We hope that through this review, we can recognize individuals and teams that have made outstanding contributions in the past year and also motivate everyone to continue their efforts in the future.

 The conference reviewed the election plan for the second General Assembly of Members proposed by Zeng Guojun, the vice president and secretary-general of the society. The election is a reflection of democracy, and we look forward to a fair and just election process. We hope that through this election, we can elect representatives who can truly represent the interests of the majority of members and jointly promote the development of the society.

 The Fourth Session of the First Council and the General Assembly of Members of the Sichuan Bioinformatics Society came to a successful conclusion! Next up was the opening ceremony of the main forum of the conference.

 President Shen Bairong delivered the opening speech for the conference. He warmly welcomed all the guests and representatives and affirmed the contributions of the Sichuan Bioinformatics Society in promoting the development of the bioinformatics field in the region and across the country. He emphasized the increasing importance of bioinformatics in the current medical and health field, especially in precision medicine, disease prevention, and treatment. President Shen also thanked all the units and individuals who supported and participated in the conference and encouraged participants to actively engage in discussions to contribute to the development of the bioinformatics field.

 Dai Han, representing the Australian Consulate General in Chengdu, delivered a speech at the conference. She first congratulated the convening of the conference and expressed Australia's expectation for further cooperation with Sichuan in the field of bioinformatics. Dai Han mentioned that with the acceleration of globalization, international scientific research cooperation has become particularly important. Australia has advanced bioinformatics research strength and rich experience and hopes to carry out more cooperation projects with Sichuan's research institutions and universities to jointly promote the development of bioinformatics research. She also emphasized the importance of education and cultural exchanges in promoting international cooperation and looked forward to more such exchanges in the future.

  Tang Yu, the Science and Technology Achievements Precision Transformation Officer from the Science and Technology Workers Service Department of the Sichuan Association for Science and Technology's Innovation Development Department, provided a detailed introduction to the Tianfu Science and Technology Cloud Services at the conference. She first elaborated on the main purpose of the Tianfu Science and Technology Cloud Services, which is to utilize advanced cloud computing technology to provide a comprehensive service platform that integrates scientific research, communication, and cooperation for scientific and technological workers, aiming to promote the precise transformation and application of scientific research achievements. Furthermore, Tang Yu introduced the innovative measures of the Tianfu Science and Technology Cloud Services in facilitating the precise transformation of scientific research achievements. Lastly, Tang Yu looked forward to the future planning of the Tianfu Science and Technology Cloud Services. She stated that with the continuous improvement of the platform's functions and the growth of its user base, the Tianfu Science and Technology Cloud will continue to expand its service scope and add more value-added services to meet the increasing demands of scientific and technological workers. She encouraged the attending researchers to actively utilize the Tianfu Science and Technology Cloud Services to maximize the value of scientific research achievements and contribute to the promotion of regional scientific and technological innovation.

 Subsequently, the opening ceremony of the main forum held an activity called "Pouring Golden Sand." The golden sand flowed down like a waterfall, shimmering with golden light. This was not just a ceremony, but also a hopeful and aspirational starting point.

 As the golden sand slowly cascaded, the conference officially commenced. In the following agenda, the attending experts will engage in in-depth exchanges and discussions on the latest research advancements, technological innovations, and industrial applications in bioinformatics. These communications and discussions will further promote academic exchange and technological innovation in the field of bioinformatics, injecting new vitality into the development of the society.

 Professor Kang Yan from West China Hospital, Sichuan University, deeply explored the application prospects and practical cases of big data and artificial intelligence technology in the field of critical care medicine with the topic "Big Data, Artificial Intelligence, and Critical Care Medicine." His presentation not only provided a wealth of information but also offered new perspectives and thoughts to the attendees.

 Professor Shi Rui from West China Hospital, Sichuan University, in his lecture titled "New Perspectives on the Role of Medical Artificial Intelligence in the High-Quality Development of Hospitals," explored the potential of artificial intelligence technology in enhancing the quality of medical services and the efficiency of hospital management. Professor Shi's research focuses on leveraging AI technology to optimize diagnostic and treatment processes, improve the accuracy of diagnoses, and enhance patient care experiences. He shared several practical application cases from West China Hospital in this field, including innovative models and application prospects of intelligent diagnostic and treatment pathways, as well as the practical application of AI technology in healthcare.

  Professor Wang Fubo from Guangxi Medical University, in his presentation titled "Research on the Application of Clinical Big Data and Artificial Intelligence in Intelligent Perception of Malignant Tumors," provided a detailed account of the development and application of clinical decision support systems for malignant tumors based on clinical big data and artificial intelligence technology. Professor Wang's lecture encompassed the screening and identification of pan-cancer and tumor-specific biomarkers, as well as research on the molecular mechanisms underlying the progression of common tumors in the urinary system and their intervention targets. His work has not only advanced the basic and clinical research on urinary system tumors but also excelled in the early diagnosis and treatment of these tumors, the "liquid biopsy" technology for malignant tumors based on extracellular vesicles, and the analysis and clinical application of medical big data.

 Professor Le Weidong from Sichuan Provincial People's Hospital presented "Intelligent Diagnosis of Alzheimer's Disease," bringing new hope to the field. His research has opened up new avenues in the diagnosis and understanding of Alzheimer's disease.

 Professor Tian Weidong shared his practical applications in the field of craniomaxillofacial surgery with digital and intelligent technologies. His lecture demonstrated the application of these technologies in surgical procedures, providing attendees with valuable practical experience.

 Professor Tian Weidong from the National Local Joint Engineering Laboratory for Oral Regenerative Medicine shared "The Application of Digital and Intelligent Technologies in Craniomaxillofacial Surgery." His presentation showcased the use of digital and intelligent technologies in surgical operations, offering attendees valuable practical insights.

 Professor Liu Yi from West China Hospital, Sichuan University, shared "The Efficacy and Mechanism of Stem Cell Therapy for Pulmonary Interstitial Fibrosis in Scleroderma." Scleroderma is an autoimmune disease that can lead to fibrosis of the skin and internal organs, severely affecting the quality of life for patients. Professor Liu provided a detailed explanation of the mechanisms of stem cell therapy, including how it can ameliorate the symptoms of scleroderma through its anti-inflammatory, anti-fibrotic, and tissue repair-promoting actions. He shared preliminary clinical trial results that demonstrated the potential of stem cell therapy in improving patients' lung function and quality of life. Professor Liu's presentation not only offered new strategies for the treatment of scleroderma but also provided insights into the application of stem cell therapy for other fibrotic diseases.

  Professor Shen Bairong from West China Hospital, Sichuan University, shared "Reverse Thinking in Medical Big Data Research." In traditional medical research, investigators typically start from known causes and explore their impact on diseases. However, the reverse thinking method proposed by Professor Shen begins with the symptoms or phenotypes of a disease and traces back to identify possible causes and mechanisms. This research approach can reveal new mechanisms and therapeutic targets that traditional methods might overlook. Through several case studies, Professor Shen demonstrated how to use big data analysis to identify key disease characteristics from complex clinical data and proposed new diagnostic and treatment strategies. His presentation provided a new perspective and methodology for the study of medical big data, inspiring the audience to think anew about data-driven medical research.

 The conference not only covered various aspects of intelligent medicine but also highlighted the significant role of bioinformatics, artificial intelligence, and big data in modern medical practice. Participants gained the latest academic information and had the opportunity to engage in in-depth exchanges and discussions with experts and scholars in the field.

 The first day of the Fourth Session of the First Council and the 2024 Annual Academic Conference of the Sichuan Bioinformatics Society has come to a successful close. The conference brought together numerous experts and scholars in the field of bioinformatics to discuss the latest advancements and future trends in intelligent medicine. The successful holding of the Council and the General Assembly of Members signifies that the Society has taken solid steps in its organizational structure and member services, laying a solid foundation for the Society's continued development. Through such academic exchange platforms, the Society will continue to promote the interdisciplinary integration of bioinformatics in clinical medicine, artificial intelligence, and big data, achieving collaborative development among multiple parties, building bridges for communication and cooperation between Society members, government, and enterprises, and fostering multi-party exchanges.

 The three-day academic conference covered a range of cutting-edge fields, including biomedical data sharing and security, critical care medicine and artificial intelligence, digital health, artificial intelligence in hematological oncology, smart vascular access, and the youth committee. The convening of this conference will further deepen our understanding of the field of intelligent medicine, explore new research directions, and stimulate innovative thinking. Participants of the conference will gain more insights into the intersection of bioinformatics with clinical medicine, artificial intelligence, and big data, thereby promoting research and application development in these related fields.